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#1 13-12-2006 00:09:05

destivic
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Date d'inscription: 30-11-2006
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Thrombocytose

La trombocytose est une anomalie de l'hémogramme caractérisée par une augmentation du nombre de plaquettes circulantes.



Diagnostic et complications


Le diagnostic est essentiellement biologique avec la découverte à l'hémogramme d'un nombre de plaquettes supérieur à 500 000/ml.

Cliniquement, on note une splénomégalie inconstante.

Les complications spécifiques d'une thrombocytose sont les hémorragies et les thromboses veineuses et artérielles.



Critères diagnostiques de la thrombocytémie essentielle


Critères diagnostiques de thrombocytémie essentielle, établis par la Polycythemia Vera Study Group en 1997:

   1. Numération des plaquettes supérieure à 600 000/mm³
   2. Hématocrite inférieur à 50 % pour un homme et 45 % pour une femme
   3. Présence de fer médullaire, ferritinémie normale ou VGM normal
   4. Pas de chromosome Philadelphie
   5. Absence de fibrose médullaire
   6. Pas d'élément cytologique d'un syndrome myélodysplasique
   7. Absence d'étiologie de thrombocytose réactionnelle



Source : encyclopédie wikipedia


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