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Un thrombus ou caillot sanguin est le produit final de la coagulation sanguine, par l'agrégation plaquettaire et l'activation du système de coagulation humorale. Un thrombus est physiologique en cas de traumatismes, mais pathologique dans d'autres cas.
La thrombose consiste en la formation d'un thrombus obturant un vaisseau sanguin.
Son détachement et sa migration dans la circulation veineuse peut entraîner des phlébites et des embolies pulmonaires.
Son détachement et sa migration dans la circulation artérielle peut entraîner infarctus et nécrose des tissus périphériques, par obstruction des artères coronaires ou des artérioles terminales.
Sortes de thrombus
- Thrombus blanc = thrombus contenant des plaquettes et des leucocytes
- Thrombus rouge = thrombus contenant des globules rouges et des plaquettes dans un réseau de fibrine ( formé à partir du thrombus blanc)
- Thrombus artériel
- Thrombus veineux
- Thrombus mural = thrombus dans les cavités du coeur ou dans la lumière de l'aorte. Habituellement attachés au mur (à la paroi) de la structure.
Source : encyclopédie wikipedia
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