Vous n'êtes pas identifié.
Molécule(s)
Daunorubicine
Classe thérapeutique
Antibiotique cytotoxique
Laboratoire(s)
Sanofi Aventis
Indications
CERUBIDINE est indiqué dans le traitement des maladies suivantes :
- lymphome hodgkinien
- lymphome non hodgkinien
- transformation aigüe de leucémie myéloïde chronique
- leucémie aigüe.
Informations pratiques
CERUBIDINE est disponible uniquement sur ordonnance.
CERUBIDINE doit être initialement prescrit à l'hôpital par des spécialistes en oncologie, les renouvellements peuvent ensuite être effectués par d'autres médecins.
CERUBIDINE se présente sous forme injectable.
Mode d'action
Le principe actif de CERUBIDINE est un antibiotique antinéoplasique cytotoxique, il agit comme un agent alkylant c'est à dire qu'il modifie la structure de l'ADN et empêche la multiplication des cellules.
En cas d'oubli
Consultez votre médecin.
Effets secondaires
CERUBIDINE peut provoquer des nausées, des vomissements, des diarrhées et des douleurs abdominales, ces effets sont fréquents mais généralement modérés.
CERUBIDINE peut colorer les urines en rouge.
CERUBIDINE a une forte toxicité cardiaque et une surveillance doit être effectuée durant le traitement.
CERUBIDINE peut également provoquer une toxicité hématologique (formule sanguine affectée et principalement leucopénie), des réactions allergiques.
Contre-indications / Précautions d'emploi
CERUBIDINE est contre-indiqué en cas d'allergie à l'un de ses composants, de grossesse, d'allaitement, et chez les sujets présentant une cardiopathie avec insuffisance cardiaque avérée.
En cas d'insuffisance hépatique (du foie) la posologie de CERUBIDINE doit être adaptée.
Il est également contre-indiqué en association avec le vaccin contre la fièvre jaune, et la phénytoïne.
Dans tous les cas, CERUBIDINE nécessite une surveillance particulière et de nombreux examens réguliers et si vous avez le moindre doute parlez en à votre médecin ou à l'équipe soignante.
Interactions médicamenteuses
CERUBIDINE est formellement contre-indiqué en association avec le vaccin contre la fièvre jaune et la phénytoïne.
De plus il est déconseillé de l'associer avec les vaccins vivants atténués, et un traitement antérieur de phénytoïne même terminé.
Une surveillance particulière doit être effectuée en cas d'association avec les anticoagulants.
Associé à la ciclosporine ou au tacrolimus, CERUBIDINE peut provoquer une immunodépression (baisse des défenses immunitaires).
Surdosage
CERUBIDINE est toxique est nécessite une surveillance particulière, si vous avez le moindre doute, faites rapidement le 15.
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