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#1 12-12-2007 10:12:18

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Caryolysine

Molécule(s)     
Chlorméthine (chlorhydrate)


Classe thérapeutique    
Cytotoxique antinéoplasique (agent alkylant, moutarde à l'azote)


Laboratoire(s)    
Genopharm


Indications    
CARYOLYSINE est un immunomodulateur, antinéoplasique cytostatique utilisé pour traiter la maladie de Hodgkin (lymphome) en polychimiothérapie.

Utilisé par voie cutanée, CARYOLYSINE est également indiqué pour traiter le psoriasis de l'adulte et le mycosis fongoïde (lymphome cutané T épidermotrope).


Informations pratiques    
CARYOLYSINE est délivré uniquement sur ordonnance.

Sa prescription et sa délivrance sont hospitalières, elles sont réservées aux spécialistes en oncologie, en dermatologie ou en hématologie ou aux médecins compétents en cancérologie.

CARYOLYSINE nécessite une surveillance particulière au cours du traitement.


Mode d'action    
La chlorméthine, principe actif de CARYOLYSINE est un immunomodulateur qui agit en altérant l'ADN des cellules cancéreuses pour les détruire.


En cas d'oubli    
Contactez votre médecin.


Effets secondaires    
Les effets indésirables de cé médicament par voie générale sont les suivants : troubles des analyses de sang, nausées, frissons, nausées, vomissements, chute de cheveux (réversible), troubles de la personalité, confusion, attaque de panique, démence, thrombophlébite.

En cas d'application locale, une irritation, des brûlures, un eczéma de contact et des démangeaisons peuvent apparaître, ces effets sont réversibles.

En cas de doute, il convient de consulter votre médecin traitant le plus tôt possible.


Contre-indications / Précautions d'emploi    
Dans le cas d'une utilisation par voie locale, CARYOLYSINE doit être dilué, il ne doit en aucun cas être utilisé pur.

CARYOLYSINE est contre-indiqué en cas d'allergie à l'un de ses composants, de grossesse et d'allaitement.

Appliquer à distance de la radiothérapie.

Un contrôle hématologique strict (numération formule sanguine) doit être effectué durant le traitement par voie générale.

CARYOLYSINE nécessite une surveillance régulière de l'hémogramme (analyse du sang).


Interactions médicamenteuses    
Pas d'interactions recensées pour CARYOLYSINE. Si vous prenez un autre médicament, signalez-le toujours au médecin ou au pharmacien.


Surdosage    
En cas de doute, contactez immédiatement le centre antipoison le plus proche.

 

#2 09-05-2010 00:18:53

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#15 21-05-2010 01:16:21

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