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Molécule(s)
Bléomycine
Classe thérapeutique
Cytotoxique antinéoplasique (antibiotique)
Laboratoire(s)
Sanofi Aventis
Indications
BLEOMYCINE est utilisé dans les traitements des cancers suivants :
- lymphomes hodgkiniens et non hodgkiniens ;
- carcinomes épidermoïdes ;
- cancer du testicule.
Informations pratiques
BLEOMYCINE est délivré uniquement sur ordonnance.
BLEOMYCINE se présente sous forme injectable par voie intraveineuse, intramusculaire ou sous cutanée.
Mode d'action
Le mécanisme d'action de BLEOMYCINE n'est pas réellementé élucidé, il semble casser le brin d'ADN empêchant ainsi les cellules cancéreuses de se multiplier.
En cas d'oubli
Contactez votre oncologue.
Effets secondaires
BLEOMYCINE entraîne une toxicité prédominant au niveau des extrémités. La peau y prend un aspect érythrosique, légèrement violacé, épaissi. Au niveau des coudes, on observe également un aspect squameux. Cette toxicité est lentement réversible à l'arrêt du traitement.
BLEOMYCINE provoque également souvent des nausées, des vomissements, des diarrhées, une perte d'appétit, un syndrome de Raynaud, des accidents thrombo-emboliques, une toux, une difficulté à respirer, une fibrose, une légère perte de cheveux.
N'hésitez pas à signaler tout effet secondaire à votre médecin.
Contre-indications / Précautions d'emploi
BLEOMYCINE est contre-indiqué en cas d'allergie à l'un des constituants, en cas de grossesse et d'allaitement.
BLEOMYCINE est également contre-indiqué en cas d'insuffisance respiratoire.
Une surveillance de la fonction pulmonaire doit être effectuée durant le traitement afin de détecter les éventuelles fibroses.
Interactions médicamenteuses
BLEOMYCINE ne doit pas être associé à la phénytoïne (à visée prophylactique) ni à la vaccination anti amarile.
Il est préférable de ne pas l'associer aux vaccins atténués vivants.
D'une façon générale signalez à votre oncologue toute traitement que vous auriez en cours.
Surdosage
Les signes du surdosage ne peuvent être distingués des effets secondaires, si vous avez le moindre doute sur la quantité prise, faites le 15 ou contactez votre médecin rapidement.
Hors ligne
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