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#1 12-12-2007 09:29:42

destivic
Administrateur
Lieu: Nantes
Date d'inscription: 30-11-2006
Messages: 140
Site web

Bicnu

Molécule(s)     
Carmustine


Classe thérapeutique    
Cytotoxique antinéoplasique (agent alkylant)


Laboratoire(s)    
Bristol-Myers Squibb


Indications    
BICNU est utilisé dans les traitements des cancers suivants :
- lymphomes hodgkiniens et non hodgkiniens ;
- myélome multiple ;
- tumeurs cérébrales primitives et secondaires ;
- mélanomes malins.


Informations pratiques    
BICNU est délivré uniquement sur ordonnance à l'hôpital.

Sa prescription et son renouvellement sont réservés aux spécialistes en oncologie ou en hématologie ou aux médecins compétents en cancérologie.

BICNU nécessite une surveillance particulière pendant le traitement, il se présente sous forme injectable par perfusion.


Mode d'action    
BICNU empêche le développement et induit sélectivement la mort des cellules cancéreuses en s'attaquant à leur ADN.


En cas d'oubli    
Contactez votre oncologue.


Effets secondaires    
BICNU provoque souvent des nausées, des vomissements, des diarrhées, des douleurs abdominales, une perte d'appétit, une aménorrhée (absence de règles), une toux, une dyspnée d'effort (difficulté à respirer), un état fébrile, une hypoxie, une alopécie (perte des cheveux), une irritation, une sensation de brûlure intense et une douleur locale au point d'injection, une augmentation du risque infectieux, une importante toxicité hématologique (atteinte des cellules du sang).

L'administration de fortes doses de BICNU peut entraîner une augmentation transitoire des transaminases, des phosphatases alcalines et de la bilirubine (enzymes du foie).

N'hésitez pas à signaler tout effet secondaire à votre médecin.


Contre-indications / Précautions d'emploi    
BICNU est contre-indiqué en cas d'allergie à l'un des constituants, en cas de grossesse et d'allaitement.

BICNU est contre-indiqué en cas de leucopénie (diminution importante du nombre de globules blancs), d'érythropénie (diminution importante du nombre de globules rouges), de thrombopénie (diminution importante du nombre de plaquettes) et chez l'enfant de moins de 5 ans.

Attention, BICNU contient de l'alcool éthylique, il est par conséquence contre-indiqué chez les personnes souffrant d'alcoolisme chronique, d'épilepsie, et d'atteinte hépatique.


Interactions
médicamenteuses    
Pas d'interactions médicamenteuses spécifiques pour BICNU.

D'une façon générale signalez à votre oncologue toute traitement que vous auriez en cours.


Surdosage    
Les signes du surdosage ne peuvent être distingués des effets secondaires, si vous avez le moindre doute sur la quantité prise, faites le 15 ou contactez votre médecin rapidement.


_________________________
*************************
L'avenir est une solution...   wink

Hors ligne

 

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